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姓名：朱书高

性别：男

职称：特聘教授

学位：博士

专业：有机化学

电子邮箱：shugaozhu@ncu.edu.cn

研究方向：活性天然产物及其类似物的合成，过渡金属催化的有机合成

科研经历

2019.7-至今 南昌大学化学化工学院 特聘教授

2017.3-2019.2 University of Utah（犹他大学）博士后 导师：Prof. Danny Hung-Chieh Chou

2015.8-2017.2 Rice University（莱斯大学）博士后 导师：Prof. K. C. Nicolaou

2012.8-2015.6中科院上海有机化学研究所博士后 导师：李昂研究员

教育背景

2007.9-2012.6浙江大学理学院化学系 有机化学博士 导师：黄宪教授

2003.9-2007.6武汉大学化学与分子科学学院 理学学士 导师：周翔教授

教学简介:有机化学

科研项目

国家自然科学基金地区项目，2023-2026

江西省第三批引进类“双千计划”入选者

代表性论文及专利:

发表论文：

1. Shugao Zhu*; Dan Wang; Shihan Liu; Yufeng Ma; Hong Wang; Yu Lan*; Ruopeng Bai; Ruwei Shen*; Palladium-Catalyzed Cross-Coupling, Divergent Allene Generation, and Cycloadditions toward Cyclobuta[b]naphthalen-3(1H)-ones and 11H-Benzo[b]fluoren-11-ones, ACS Catalysis, 2023, 13(13): 8402–8412.

2. Wenliang Huang; Hong Wang; Bin Liu*; Ruwei Shen*; Shugao Zhu*; Synthesis of 1,1,4,5-Tetrasubstituted Phthalans via Pd-Catalyzed Three-Component Reactions of Haloarenes, Alkynes, and Protic Nucleophiles, Oganic Letters, 2022, 24(47): 8651−8656.

3. Li, Xiaojie; Xiao, Tianyu; He, Guangke; Zhu, Shugao; Zhu, Dunru; Shen, Ruwei*; Pyrrolidine-Catalyzed Annulations of Quinone Monoacetals with Naphthols: Synthesis of 2-Oxabicyclo[3.3.1]nonane Skeletons, Transformations and Reaction Mechanism, Advanced Synthesis & Catalysis, 2022, 364(3): 622-636.

4. K. C. Nicolaou*; Pengxi Chen; Shugao Zhu; Quan Cai; Rohan D. Erande; Ruofan Li; Hongbao Sun; Kiran Kumar Pulukuri; Stephan Rigol; Monette Aujay; Joseph Sandoval; Julia Gavrilyuk; Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues, Journal of the American Chemical Society, 2017, 139(43): 15467-15478.

5. Yong Li#; Shugao Zhu#; Jian Li; Ang Li*; Asymmetric Total Syntheses of Aspidodasycarpine, Lonicerine, and the Proposed Structure of Lanciferine, Journal of the American Chemical Society, 2016, 138(12): 3982-3985.

6. Nicolaou K C*; Cai Quan; Sun Hongbao; Qin Bo; Zhu Shugao; Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7"-epi-C and Full Structural Assignment of Trioxacarcin C, Journal of the American Chemical Society, 2016, 138(9): 3118-3124.

7. Shen Ruwei*; Yang Jianjun; Zhu Shugao; Chen Chao; Wu Luling; Gold(I)-Catalyzed Decarboxylation of Propargyl Carbonates: Reactivity Reversal of the Gold Catalyst from pi-Lewis Acidity to sigma-Lewis Acidity, Advanced Synthesis & Catalysis, 2015, 357(6): 1259-1269.

8. Zhu Shugao; Wu Luling*; Huang Xian; Gold-Catalyzed Cyclization of 3-(2 '-Azidoaryl)-1-arylpropargyl Carbonates or 3-Aryl-1-(2 '-azidoaryl)propargyl Carbonates to Produce Quinolines, Journal of Organic Chemistry, 2013, 78(18): 9120-9126.

9. Jianfeng Xu; Shugao Zhu; Luling Wu*; Xian Huang; Chemoselective synthesis of highly substituted 1,2-allenyl ketones, furans, and 2-alkynyl ketones from reaction of lithium selenolates with 1-(1-alkynyl) cyclopropyl ketones and electrophiles, Organic and Biomolecular Chemistry, 2012, 10(18): 3705-3714.

10. Zhu Shugao; Wu Luling*; Huang Xian; Palladium-catalyzed sequential reaction via Sonogashira coupling, isomerization, Claisen rearrangement and [4 2] cycloaddition sequence for the rapid synthesis of tricyclo[3.2.1.0(2,7)]oct-3-ene derivatives, RSC Advances, 2012, 2(1): 132-134.

11. Zhu Shugao; Wu Luling*; Huang Xian; Palladium(0)-catalyzed cyclization of 1,6-diyn-3-yl carbonates with a nucleophilic functionality: efficient synthesis of polycyclic benzo[b]fluorene derivatives via allene intermediates, Organic and Biomolecular Chemistry, 2012, 10(18): 3696-3704.

12. Shugao Zhu; Jian Cao; Luling Wu*; Xian Huang; Synthesis of Polycyclic Isoindoline Derivatives via Tandem Pd-Catalyzed Coupling, Propargyl-Allenyl Isomerization, [4 2] Cycloaddition and Aromatization Reaction, Journal of Organic Chemistry, 2012, 77(22): 10409-10415.

13. Ruwei Shen; Shugao Zhu; Xian Huang*; Unexpected Pd-Catalyzed Coupling, Propargyl-Allenyl Isomerization and Alder-Ene Reaction: Facile Synthesis of Some Not Readily Available 2,3-Dihydrofuran Derivatives, Journal of Organic Chemistry, 2009, 74(11): 4118-4123.

14. Xian Huang*; Shugao Zhu; Ruwei Shen; Palladium-Catalyzed Sequential Reactions via Allene Intermediates for the Rapid Synthesis of Fused Polycyclic Pyrrole Derivatives, Advanced Synthesis & Catalysis, 2009, 351(18): 3118-3122.

15. Weng Xiaocheng; Ren Lige; Weng Liwei; Huang Jing; Zhu Shugao; Zhou Xiang*; Weng Linhong; Synthesis and biological studies of inducible DNA cross-linking agents, Angewandte Chemie International Edition, 2007, 46(42): 8020-8023.

专利：

1. Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogs Thereof.

K. C. Nicolaou*, P. Chen, S. Zhu, Q Cai. PCT Int. Appl. (2019), WO 2019036537 A1 20190221.