Name: Xiaojun Zeng

Gender: Male

Job title: Professor.

Email Address: xjzeng@ncu.edu.cn

Education and Work Experience ：

2020.07 -- present: School of Chemistry and Chemical Engineering, Nanchang University, Professor, Director of …….

2019.04~2020.07: Miami University, Postdoctoral Researcher

2018.06~2019.03: University of Louisville, Postdoctoral degree

2014.04~2015.06: South University of Science and Technology of China. Research assistant

2015.09~2018.07: Donghua University, doctoral degree

2010.09~2013.07: Zhejiang Normal University, Master degree

2006.09~2010.07: Jinggangshan University, Bachelor degree

Teaching：

Organic Chemistry, University Chemistry.

Research fields:

Our research group primarily concentrates on catalytic chemistry, with a particular emphasis on exploring straightforward and efficient synthesis strategies. We employ free radicals as carriers to precisely achieve the rapid assembly of fluorine-containing compounds.

Group website: https://www.x-mol.com/groups/zeng_xiaojun?lang=en

Google Scholar: https://scholar.google.com/citations?user=b5Q3nVgAAAAJ&hl=en

Research projects：

2021.01-2023.12 Natural Science Foundation of Jiangxi province

2022.01-2024.12  National Natural Science Foundation of China

2023.01-2023.12 Jiangxi Province Overseas Shortage Talent Project

2024.01-2027.12  National Natural Science Foundation of China

Awards and Honors：

Representative papers and patents：

1. Jiang, X.; Liu, B.; Li, C.; Wen, X.; Zeng, X*. SN2′-Type Difluoro- and Perfluoroalkylation of gem-Dichlorocyclobutenones Mediated by (DMPU)₂Zn(Rf)₂. Org. Lett. 2025,27, 11940–11945

2.Du, Z.;^# Gong, W.;^# Yuan, S.; Ren, Y.; Huang, C.; X, Zeng*.Copper-Catalyzed Difluoromethylation of Alkenyl Thianthrenium Salts.  Org. Lett. 2024, 26, 11062–11066

3. Jiang, X.; Gong, W.; Li, X.; Wang, S.; Gu, Z.; Yang, Y.; Zeng, X* Pd-Catalyzed Divergent Site-Selective Difluoromethylation and Difluoromethylcarbonylation of Aryl Sulfonium Salts. ACS Catal. 2024, 13557-13566.

4. J,Han*.; X,Lu.; L,Chen.; K,Gong.; B,Xu*.; X, Zeng*(Radio)Fluoro-iodination of Alkenes Enabled by a Hydrogen Bonding Donor Solvent. Org.Lett.2024,26, 3435-3440.

5.Du, Z.;^# Liu, S.;^# Li, Y.; Peng, J.; Sun, Y.; Song, Y.; Liu, Y.; Zeng, X*. Fluoroamide-Directed Regiodivergent C-Alkylation of Nitroalkanes. Org. Lett. 2023,25, 4632–4637

6.Zeng, X^#.; Wang, C^#.; Yan, W^#.; Rong, J^#.; Song, Y^#.; Xiao, Z.; Cai, A.; Liang, S. H*.; Liu, W*. Aryl Radical Enabled, Copper-Catalyzed Sonogashira-Type Cross-Coupling of Alkynes with Alkyl Iodides. ACS Catal. 2023, 2761-2770. 

7.Man, Y.; Liu, S.; Xu, B*.; Zeng, X*., N-Heterocyclic-Carbene-Catalyzed C–H Acylation via Radical Relay. Org. Lett. 2022,24,944-948.

8.Zeng, X.; Liu,S.; Hao,Y.; Yi,Y.; Hammond, G. B*.; Xu, B*, “Widely Applicable Regio- and Stereoselective Synthesis of 1,2-Dihaloalkenes Using in situ Generated ICl, IBr, BrCl, I₂, and Br₂” Chem, 2020,6,1018-1031.

9.Zeng, X.⁺; Yan, W⁺.; Paeth, M.; Zacate, S. B.; Cai.A, Wang Y.; Yang, D.; Yang, K.; Liu, W*., “Copper-Catalyzed Deaminative Difluoromethylation”. ”Angew. Chem. Int. Ed. 2020, 59, 16398-16403.

10.Zeng, X.; Yan, W.; Paeth, M.; Zacate, S. B.; Hong, P.-H.; Wang, Y.; Yang, D.; Yang, K.; Yan, T.; Song, C.; Cao, Z*.; Cheng, M.-J.; Liu, W*., Copper-Catalyzed, Chloroamide-Directed Benzylic C−H Difluoromethylation. J. Am. Chem. Soc. 2019, 141, 19941-19949.

11.Zeng, X.; Yan, W.; Zacate, S. B.; Chao, T.-H.; Sun, X.; Cao, Z*.; Bradford, K. G. E.; Paeth, M.; Tyndall, S. B.; Yang, K.; Kuo, T.-C.; Cheng, M.-J.; Liu, W*., "Copper Catalyzed Decarboxylative Difluoromethylation". J. Am. Chem. Soc. 2019, 141, 11398-11403

12.Zeng, X.; li,J.; Hammond, G. B*.; Xu, B*, “Nucleophilic (Radio)Fluoro-Click Reaction Enabled by Hydrogen Bonding Clusters” Angew. Chem. Int. Ed. 2018, 57, 2924-2928.

13.Zeng, X.; Liu, S.; Shi, Z.; Liu, G.; Xu, B*. “Synthesis of α-Fluoroketones by Insertion of HF into a Gold Carbene” Angew. Chem. Int. Ed. 2016, 55, 10032-10036.