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刘美英
讲师
博士
化学
lmy5305@iccas.ac.cn
仿生智能纳米材料






2014/11- 南昌大学,化学学院


2012/06-2014/10 中国科学院化学研究所,博士后,导师:江雷院士


2008/04-2011/07 中国科学院上海微系统与信息技术研究所,博士,导师:赵建龙 研究员


2004/09-2006/07 暨南大学,药学院,硕士


1999/09-2004/07 江西医学院 学士


刘美英,女,博士。主要研究方向:聚集诱导发光染料合成、探针构建及生物医学应用,仿生纳米通道设计合成。近5 年来以Advanced Functional Materials, Analytical ChemistryBiosensors and Bioelectronic, Nanoscale, Polymer Chemistry, Journal of Materials Chemistry B等杂志上发表论文60篇,文章引用1500余次,H因子21,申请专利4项。

(1) 国家自然科学基金地区项目,项目编号:21561022,项目名称:基于非对称浸润性的仿生纳米通道:智能门控机理和器件研究,主持。

(2) 江西省自然科学基金面上项目,项目编号:20161BAB203072,项目名称:基于非对称修饰的仿生智能纳米孔道研究,主持

(3) 江西省自然科学基金青年项目,项目编号:20161BAB213066,项目名称:基于聚集诱导发光染料和功能核酸的重金属离子传感研究,主持

(4) 中国博士后科学基金特别资助项目项目编号:2013T60178,项目名称:基于生物分子修饰的纳米通道的选择性离子泵研究,主持。

(5) 中国博士后科学基金面上项目,项目编号:2012M520388,项目名称:基于纳米通道和功能核酸的重金属离子传感器研究,主持。

(6)  省级教改课题,项目编号:JXJG-17-1-59,项目名称:“双一流”背景下理工科大学生科研素质和人文素质培养的实践和探索,参与。

(7) 校级教改课题,项目编号:NCUJGLX-17-42,项目名称:“以学生为中心”的大学化学科研和创新训练的探索与实践,参与。














[1] Meiying Liu, Huacheng Zhang, Kan Li, Liping Heng, Shutao Wang, Ye Tian*, Lei Jiang*. A Bio-inspired Potassium and pH Responsive Double-gated Nanochannel. Advanced Functional Materials, 2015; 25(3):421-426.

[2]  Meiying Liu, Chunping Jia, Yunyan Huang, Xinhui Lou, Shihua Yao, Qinghui Jin, Jianlong Zhao, and Jiaqing Xiang. Highly sensitive protein detection using enzyme-labeled gold nanoparticle probes. Analyst, 2010; 135(2):327-331.

[3] Meiying Liu, Chunping Jia, Qinghui Jin, Xinhui Lou, Shihua Yao, Jiaqing Xiang, and Jianlong Zhao. Novel colorimetric enzyme immunoassay for the detection of carcinoembryonic antigen. Talanta, 2010; 81(4-5):1625-1629.

[4] Meiying Liu, Min Yuan, Xinhui Lou, Hongju Mao, Dongmei Zheng, Ruxing Zou, Nengli Zou, Xiangrong Tang, and Jianlong Zhao. Highly effective label-free optical detection of single nucleotide polymorphisms by the combination of nuclease and gold nanoparticles. Biosensor and Bioelectronics, 2011, 26(11): 4294-4300.

[5] Meiying Liu, Xinhui Lou, Juan Du, Ming Guan, Jing Wang, Xiaofan Ding and Jianlong Zhao. DNAzyme-based fluorescent microarray for highly selective and sensitive detection of lead (II). Analyst, 2011, 137: 70-72.

[6] Juan Du, Meiying Liu (contributed equally), Xinhui Lou, Tao Zhao, Zheng Wang, Ying Xue, Jianlong Zhao, and Yuanshen Xu. Highly sensitive and selective chip-based fluorescent sensor for mercuric ion: development and comparison of turn-on and turn-off systems. Analytical Chemistry, 2012, 84 (18): 8060-8066.

[7] Xiqi Zhang, Meiying Liu (contributed equally), Bin Yang, Xiaoyong Zhang, Yen Wei. Tetraphenylethene-based aggregation induced emission fluorescent organic nanoparticles: Facile preparation and cell imaging application. Colloids and surfaces B: Biointerfaces, 2013, 112(12): 81-86.

[8] Xiqi Zhang, Meiying Liu (contributed equally), Bin Yang, Xiaoyong Zhang, Zhenguo Chi, Siwei Liu, Jiarui Xu, Yen Wei. Cross-linkable aggregation induced emission dye based red fluorescent organic nanoparticles and their cell imaging applications. Polymer Chemistry, 2013, 4(19):5060-5064.

[9] Meiying Liu, Xiqi Zhang, Bin Yang, Fengjie Deng, Jinzhao Ji, Yang Yang, Zengfang Huang, Xiaoyong Zhang*, Yen Wei*. Polylysine Cross-linked AIE Dye Based Fluorescent Organic Nanoparticles for Biological Imaging Applications. Macromolecular Bioscience, 2014, 14(9):1260-1267.

[10] Meiying Liu, Xiqi Zhang, Bin Yang, Liangji Liu, Fengjie Deng, Xiaoyong Zhang*, Yen Wei*. Luminescence Tunable Fluorescent Organic Nanoparticles from Polyethyleneimine and Maltose: Facile Preparation and Bioimaging Applications. RSC Advances, 2014, 4(43):22294-22298.

[11] Meiying Liu, Xiqi Zhang, Bin Yang, Fengjie Deng, Yang Yang, Zhen Li, Xiaoyong Zhang*, Yen Wei*. Preparation and Bioimaging Applications of AIE Dye Cross-linked Luminescent Polymeric Nanoparticles.Macromolecular Bioscience, 2014, 14(12):1712-1718.

[12] Meiying Liu, Xiqi Zhang, Bin Yang, Fengjie Deng, Zengfang Huang, Yang Yang, Zhen Li, Xiaoyong Zhang*, Yen Wei*. Ultrabright and Biocompatible AIE Dye Based Zwitterionic Polymeric Nanoparticles for Biological Imaging. RSC Advances, 2014, 4(66):35137-35143.

[13] Meiying Liu, Xiqi Zhang, Fengjie Deng, Zhen Li, Junchao Wei, Xiaoyong Zhang*, Yen Wei*. Water Dispersible, Non-cytotoxic, Cross-linked Luminescent AIE Dots: Facile Preparation and Bioimaging Applications. Applied Surface Science, 2014, 322:155-161.

[14] Meiying Liu, Xiqi Zhang, Bin Yang, Zhan Li, Fengjie Deng, Yang Yang, Xiaoyong Zhang*, Yen Wei*.Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging.Carbohydrate Polymers, 2015, 112: 49-55.

[15] Meiying Liu, Jinzhao Ji, Xiaoyong Zhang*, Xiqi Zhang, Bin Yang, Fengjie Deng, Zhen Li, Ke Wang, Yang Yang, Yen Wei*. Self-polymerization of Dopamine and Polyethyleneimine: Novel Fluorescent Organic Nanoprobes for Biological Imaging Applications. Journal of Materials Chemistry B, 2015, 3: 3476-3482.

[16] Meiying Liu, Hongye Huang, Ke Wang, Dazhuang Xu, Qing Wan, Jianwen Tian, Qiang Huang, Fengjie Deng, Xiaoyong Zhang*, Yen Wei*. Fabrication and Biological Imaging Application of AIE-active Luminescent Starch based Nanoprobes. Carbohydrate Polymers, 2016, 142: 38-44.

[17] Chunning Heng, Meiying Liu (contributed equally), Pengfei Wang, Ke Wang, Xiaoyan Zeng, Daidi Fan, Junfeng Hui*, Xiaoyong Zhang*, Yen Wei*. Preparation of silica nanoparticles based multifunctional therapeutic systems via one-step mussel inspired modification. Chemical Engineering Journal, 2016, 296: 268-276.

[18] Peng Gao, Meiying Liu (contributed equally), Jianwen Tian, Fengjie Deng, Ke Wang, Dazhuang Xu, Liangji Liu, Xiaoyong Zhang*, Yen Wei*. Improving the drug delivery characteristics of graphene oxide based polymer nanocomposites through the “one-pot” synthetic approach of single-electron-transfer living radical polymerization. Applied Surface Science, 2016, 378: 22-29.

[19] Zi Long, Meiying Liu (contributed equally), Ke Wang, Fengjie Deng, Dazhuang Xu, Liangji Liu, Yiqun Wan, Xiaoyong Zhang*, Yen Wei*. Facile Synthesis of AIE-active Amphiphilic Polymers: Self Assembly and Biological Imaging Applications. Materials Science & Engineering: C-Materials for Biological Applications, 2016, 66: 215-220.

[20] Qing Wan, Meiying Liu (contributed equally), Dazhuang Xu, Hongye Huang, Liucheng Mao, Guangjian Zeng, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Facile Fabrication of Amphiphilic AIE active Glucan via Formation of Dynamic Bonds: Self Assembly, Stimuli Responsiveness and Biological Imaging. Journal of Materials Chemistry B, 2016, 4(22): 4033-4039.

[21] Guangjian Zeng, Meiying Liu (contributed equally), Xinhua Liu, Qiang Hunag, Dazhuang Xu, Liucheng Mao, Hongye Huang, Fengjie Deng, Xiaoyong Zhang*, Yen Wei. Mussel inspired preparation of MoS2 based polymer nanocomposites: The case of polyPEGMA. Applied Surface Science, 2016, 387: 399-405.

[22] Qiang Hunag, Meiying Liu (contributed equally), Junyu Chen, Ke Wang, Dazhuang Xu, Liucheng Mao, Fengjie Deng, Hongye Huang, Xiaoyong Zhang*, Yen Wei*. Enhanced Removal Capability of Kaolin towards Methylene Blue by Mussel-inspired Functionalization. Journal of Materials Science, 2016, 51(17): 8116-8130.

[23] Hongye Huang, Meiying Liu (contributed equally), Songsong Luo, Ke Wang, Qing Wan, Fengjie Deng, Dazhuang Xu, Xiaoyong Zhang*, Yen Wei*. One-step preparation of AIE-active dextran via formation of phenyl borate and their bioimaging application. Chemical Engineering Journal, 2016, 304: 149-155.

[24] Qiang Huang, Meiying Liu (contributed equally), Junyu Chen, Ke Wang, Dazhuang Xu, Fengjie Deng, Hongye Huang, Xiaoyong Zhang*, Yen Wei*. Mussel Inspired Preparation of Functional Silica Nanocomposites for Environmental Adsorption Applications. Applied Surface Science, 2016, 387: 285-293.

[25] Zi Long, Meiying Liu (contributed equally), Qing Wan, Liucheng Mao, Hongye Huang,  Guangjian Zeng, Yiqun Wan, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Facile Fabrication of PEGylated Fluorescent Organic Nanoparticles with Aggregation Induced Emission Feature via Formation of Dynamic Bonds and Their Biological Imaging Applications. Macromolecular Rapid Communications, 2016, 37(20): 1657-1661.

[26] Qiang Huang, Meiying Liu (contributed equally), Fengjie Deng, Ke Wang, Hongye Huang, Dazhuang Xu, Guangjian Zeng, Xiaoyong Zhang*, Yen Wei*. Mussel inspired preparation of amine-functionalized Kaolin for effective removal of heavy metal ions. Materials Chemistry and Physics, 2016, 181:116-125.

[27] Qing Wan, Meiying Liu (contributed equally), Dazhuang Xu, Liucheng Mao, Hongye Huang, Peng Gao, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Fabrication of Amphiphilic Fluorescent Nanoparticles with AIE Feature via One-pot Clickable Mercaptoacetic Acid Locking Imine Reaction: Synthesis, Self-Assembly and Bioimaging. Polymer Chemistry, 2016, 7(27): 4559-4566.

[28] Hui Xu, Meiying Liu (contributed equally), Ming Lan, Huaying Yuan, Weijen Yuan, Jianwen Tian, Qing Wan, Xiaoyong Zhang*, Yen Wei*. Mussel Inspired PEGylated Carbon Nanotubes: Biocompatibility Evaluation and their Drug Delivery Applications. Toxicology Research, 2016, 5(5): 1371-1379.

[29] Qiang Huang, Meiying Liu (contributed equally), Ren Guo, Liucheng Mao, Qing Wan, Guangjian Zeng, Hongye Huang, Fengjie Deng, Xiaoyong Zhang*, Yen Wei*. Facile synthesis and characterization of poly(levodopa) modified silica nanocomposites via selfpolymerization of levodopa and their adsorption behavior towards Cu2+. Journal of Materials Science, 2016, 9625-9637.

[30] Qing Wan, Meiying Liu (contributed equally), Dazhuang Xu, Liucheng Mao, Jianwen Tian, Hongye Huang, Peng Gao, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Fabrication of aggregation induced emission active Luminescent Chitosan Nanoparticles via a “one-pot” Multicomponent Reaction. Carbohydrate Polymers, 2016, 152: 189-195.

[31] Yun Xue, Meiying Liu (contributed equally), Hongye Huang, Fengjie Deng, Guangjian Zeng, Qing Wan, Shangdong Liang*, Xiaoyong Zhang*, Yen Wei*.  Facile preparation, through Schiff base formation, of luminescent amphiphilic carbohydrate polymers with aggregation-induced emission characteristics for biological imaging. RSC Advances, 2016, 6(79): 76011-76016.

[32] Zi Long, Meiying Liu (contributed equally), Qing Wan, Liucheng Mao, Hongye Huang, Guangjian Zeng, Yiqun Wan, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Ultrafast preparation of AIE-active fluorescent organic nanoparticles via a "one-pot" microwave-assisted Kabachnik-Fields reaction. Macromolecular Rapid Communications, 2016, 37(21):1754-1759.

[33] Meiying Liu, Guangjian Zeng, Ke Wang, Qing Wan, Lei Tao, Xiaoyong Zhang*, Yen Wei*. Recent Development of Polydopamine: An Emerged Soft Matter for Surface Modification and Biomedical Applications. Nanoscale, 2016, 8(38):16819-16840.

[34] Qing Wan, Meiying Liu (contributed equally), Yili Xie, Jianwen Tian, Qiang Huang, Fengjie Deng, Liucheng Mao, Qingsong Zhang, Xiaoyong Zhang*, Yen Wei. Facile and Highly Efficient Fabrication of Graphene Oxide based Polymer Nanocomposites through Mussel Inspired Chemistry and Their Environmental Pollutant Removal Application. Journal of Materials Science, 2017, 52(1):504-518.

[35] Guangjian Zeng, Meiying Liu (contributed equally), Kexin Shi, Chunning Heng, Liucheng Mao, Qing Wan, Hongye Huang, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Surface modification of nanodiamond through metal free atom transfer radical polymerization. Applied Surface Science, 2016, 390: 710-717.

[36] Zi Long, Meiying Liu (contributed equally), Ruming Jiang, Qing Wan, Liucheng Mao, Yiqun Wan, Fengjie Deng*, Xiaoyong Zhang*, Yen Wei*. Preparation of water soluble and biocompatible AIE-active fluorescent organic nanoparticles via multicomponent reaction and their biological imaging capability. Chemical Engineering Journal, 2017, 308: 527-534.